
Does Prednisone Affect STI Blood Tests? What You Need to Know
September 25, 2025How often should you get STI tested? Learn the CDC’s guidelines, when more frequent testing makes sense, and what to discuss with your provider.
STIs (sexually transmitted infections) can be sneaky — many people have them without any symptoms at all. That’s why testing regularly is one of the most important things you can do for your health (and your partner’s). But how do you know what “regularly” really means?
If you’ve ever wondered how often should you get STI tested, you’re not alone. The answer depends on your age, lifestyle, and relationship status — but the good news is, the guidelines are clear.
Let’s break it down.
What the CDC (and Experts) Recommend
The Centers for Disease Control and Prevention (CDC) has developed recommendations for STI testing frequency based on age, sex, and risk level. These guidelines help you understand what schedule is right for you.
Here’s what the CDC suggests:
Chlamydia and Gonorrhea: People who are AFAB (assigned female at birth) and under 25, or who have a cervix and risk factors such as new or multiple sexual partners, should get tested at least once a year. People who are AMAB (assigned male at birth) and sexually active should also include regular testing as part of their routine care.
For men who have sex with men (MSM), the CDC recommends annual screening at all potential exposure sites (urine, rectal, and throat). Those with multiple or anonymous partners should test every 3–6 months. Heterosexual individuals with new or multiple partners or other risk factors should talk with their healthcare provider about testing frequency.
HIV: Everyone ages 13–64 who is sexually active should have at least one HIV test as part of routine healthcare. People living with HIV should be tested at their initial evaluation and at least once a year thereafter.
Hepatitis C (Hep C): The CDC recommends that all adults ages 18–79 get screened for Hep C at least once, regardless of risk. Individuals with ongoing risk factors—such as injection drug use or multiple sexual partners—may need more frequent testing.
These are baselines — not limits. Depending on your activity, health history, or changes in your relationships, your provider might recommend more frequent testing.
When More Frequent Testing Makes Sense
Even if you’re already getting tested once a year, there are certain times when you should go in sooner.
Think of STI testing like routine maintenance — the more you check, the less likely you are to miss something important. You may want to increase your testing frequency if:
- You have multiple or anonymous sexual partners
- You or your partner(s) don’t consistently use condoms
- You or your partner recently had an STI
- You’re starting a new sexual relationship
- You’re taking PrEP or live in an area with high HIV prevalence
- You notice symptoms like unusual discharge, sores, or pain
In these cases, most experts — including the CDC — recommend getting tested every 3–6 months. It’s a simple step that can make a huge difference in catching and treating infections early.
How to Use This Information in Real Life
Knowing how frequently to get tested for STIs is one thing — putting it into practice is another. Here’s how to make regular testing a simple, stress-free part of your health routine:
- Start with a baseline. Even if you feel healthy, get tested at least once a year. You can have testing done at your yearly primary care appointment!
- Adjust based on risk. More partners or new relationships? Get tested more often.
- Talk to your provider. They’ll recommend which tests you need and how often.
- Set reminders. Add a recurring note in your phone or calendar every 6–12 months.
And remember, STI testing isn’t something to be embarrassed about. It’s a sign that you’re taking control of your health and protecting others, too.
FAQ: How Often Should You Get STI Tested?
Do I need to test for every STI each time?
Not always. Your provider will choose tests based on your exposure risks — for example, chlamydia and gonorrhea for most people, plus HIV and syphilis depending on your history.
Can I wait until I have symptoms to get tested?
It’s better not to. Many STIs have no symptoms early on, and waiting could allow the infection to spread or cause complications.
Does being in a monogamous relationship mean I can stop testing?
If both partners have tested negative and are exclusive, you may be able to test less frequently — but new relationships or any potential exposure warrant another test.
How soon after a possible exposure should I test?
That depends on the infection. Chlamydia and gonorrhea tests can detect infection within days, while HIV and syphilis may require several weeks for accurate results. When in doubt, test and then retest after the “window period.”
Are STI tests covered by insurance or available for free?
Most clinics — including many community health centers — offer low-cost or no-cost STI testing, even if you don’t have insurance.
Take Control of Your Sexual Health
Regular STI testing is simple, quick, and one of the best ways to protect your long-term health. Whether you’re due for your annual screening or want to check in more often, getting tested gives you peace of mind and helps stop infections before they spread.
If you live in Central Florida, Harmony Healthcare offers confidential, no-cost STI testing and treatment in Orlando, Tampa, and Kissimmee. Contact us today to schedule an appointment — we’ll take great care of you, every step of the way.






